The Healthcare Compliance Packaging Council celebrating 25 years

The Healthcare Compliance
Packaging Council

Compliance-prompting Research

HCPC actively supports third party research aimed at demonstrating the potential impact of compliance prompting packaging, including benefits to patients and reduced healthcare costs. We also report on such research as it becomes available. Below is a description of current research available from our website.

Current Research Results

The Novartis 2010 Compliance Package of the Year, DiovanHCT® Shellpak® is featured in a peer reviewed journal, Patient Preference & Adherence. In it, Novartis and Xcenda present an analysis of the results of the deployment of this package at Walmart. The research shows very significant improvements in patient persistence and medication possession ratio for hypertensive women over 60 years of age.

Contract packed by AndersonBrecon on behalf of Novartis Pharmaceuticals, the Diovan HCT® Shellpak™ features 30 days of treatment in a calendarized unit dose blister format. To facilitate compliance with the medication regimen, tablets are laid out with color coded days and weeks, including reminders for refilling the prescription. The 30 day blister is contained in the 170mm Shellpak™ outer, a patented child resistant package design from MWV. The rigid plastic design features a front and back label. The back label provides the designated area for the patient's prescription label as well as an adhered prescription insert. The front of the pack features an extended content booklet label, including a photograph of the pill. Multiple pages within the front label provide patients assistance with dosing instructions, guides to joining the BP Success Zone Program including both the website and toll-free number, and additional regulatory information.

The Diovan HCT® Shellpak™ is offered in four strength combinations. Each strength combination features a distinctive color (Brown, Blue, Purple, Red) and photograph of the unique tablet design for each strength to ensure correct dosing for the patient.

Through permission of Dovepress, you can download the paper, "Real-world impact of reminder packaging on antihypertensive treatment adherence and persistence," from Patient Preference and Adherence from the HCPC website. Click here to download the paper.



HCPC Whitepaper Covers 20+ Years of Studies that Support Improved Patient Adherence through Compliance-Prompting Packaging.


The US Healthcare System is heading for a dramatic overhaul. Projects targeting improvement of care and cost reduction are well underway. Data suggests that poor medication adherence has a detrimental effect on the healthcare, contributing to the increasing problem of poor outcomes. Improving medication adherence is critical and many organizations are looking for adherence solutions. Unfortunately, pharmaceutical prescription packaging is not often targeted in these activities and has been largely untouched for more than 55 years. The research results reported within this HCPC White paper support the need to address this!

Download the HCPC White paper now!


Compliance Facts

A poll released by Prescriptions for a Healthy America: A Partnership for Advancing Medication Adherence. and conducted by Greenberg Quinlan Rosner Research and Public Opinion Strategies found that two-thirds of patients prescribed medication do not take the medication as intended.
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Taking Medicines as Prescribed Can Lower Costs and Improve Health Outcomes PhRMA, Jan 2011
This document from PhRMA, provided with their permission, discusses the difference between primary and secondary nonadherence and covers chronic conditions nonadherence, predictors of nonadherence and the increased costs resulting from nonadherence. The paper also provides some steps that organizations are utilizing to improve adherence.


This PhRMA document, provided with their permission, summarizes research assessing the impact of the Medicare Part D program on beneficiaries' use of other medical care and then review several studies showing that the presence of prescription drug coverage is associated with better outcomes and lower costs among large populations, cutting across many conditions. The remainder of the paper surveys the extensive literature documenting the association between appropriate medication use and improved clinical and economic outcomes across specific chronic conditions.

HCPC’s Innovative Design winner of the 2009 Compliance Package of the Year, VitalityTM GlowCapTM, shared some recent compelling cost savings figures that should help drive adherence packaging, in any form. Click here to see an edited version of their presentation created by David Rose, Vitality CEO.

An Ohio State University study concludes that packaging can help improve compliance and treatment outcomes. To learn more about this study, click here to access a presentation provided by Philip J. Schneider, M.S., F.A.S.H.P., Clinical Professor, College of Pharmacy, The Ohio State University, presented at an HCPC Symposium.